Clinical Studies

Review evidence demonstrating the impact continuous glucose monitoring (CGM) use can have on glycemic control and variability.

Evidence for Benefits of CGM Use

Recognized as a standard of care in diabetes management by the American Diabetes Association (ADA), American Association of Clinical Endocrinologists (AACE) and the Endocrine Society,^1,2,3 continuous glucose monitoring (CGM) use has proven to both reduce A1C and time spent in hypoglycemia regardless of delivery method.^4,5 Regular CGM use is also associated with an increase of time spent in range,^4,6 a reduction of severe hypoglycemic incidents,^7,8 and associated with many behavioral changes that promote significant positive change in diabetes self-management.⁹

Resources

The Potential Impact of Continuous Glucose Monitoring Use on Diabetes-Related Attitudes and Behaviors in Adults with Type 2 Diabetes: A Qualitative Investigation of the Patient Experience

Topic: Behavior Change, Type 2 Diabetes, Lifestyle Modification Key question: Could glucose sensor use lead the individual to make significant dietary or activity changes, or perhaps encourage optimal...

Clinical Studies

Continuous glucose monitoring for glycaemic control and cardiovascular risk reduction in patients with type 2 diabetes not on insulin therapy

Topics: Type 2 Diabetes, Cardiovascular Outcomes, Behavior Change Key question: What are the potential benefits of widening the application of glucose sensors in type 2 diabetes? Research Spotlight:...

Clinical Studies

The Dexcom Community Glucose Monitoring Project: Six-Month Results Using Continuous Glucose Monitoring in Type 2 Diabetes

Topic: Type 2 Diabetes, Primary Care, Lifestyle Modification Key question: What are the benefits of a glucose sensor in type 2 diabetes in a real-world primary care setting? Research Spotlight: “The...

Clinical Studies

Glycemic excursion minimization in the management of type 2 diabetes: a novel intervention tested in a randomized clinical trial

Topic: Type 2 Diabetes, Lifestyle Modification, Post-Prandial Glucose Key question: Is minimizing glycemic excursions as effective as weight loss in reducing A1C in adults with T2D? Research Spotlight...

Clinical Studies

The Legacy Effect in Type 2 Diabetes: Impact of Early Glycemic Control on Future Complications (The Diabetes & Aging Study)

Topic: Type 2 Diabetes, Newly Diagnosed, Early Initiation Key question: Does the glycemic legacy effect begin as early as the 1st year in real-world populations? Research Spotlight: “The Legacy Effect...

Clinical Studies

CGM initiation within 1st year of diagnosis proven to reduce A1C

Continuous Glucose Monitoring Initiation Within First Year of Type 1 Diabetes Diagnosis Is Associated With Improved Glycemic Outcomes: 7-Year Follow-Up Study Anagha Champakanath, Halis Kaan Akturk, G...

Clinical Studies

1 American Diabetes Association. Glycemic Targets: Standards of Medical Care in Diabetes-2018. Diabetes Care. 2018;41(Suppl 1):S55-S64.

2 Bailey TS, Grunberger G, Bode BW, et al. American Association of Clinical Endocrinologists and American College of Endocrinology 2016 Outpatient Glucose Monitoring Consensus Statement. Endocr Pract. 2016;22(2):231-261.

3 Peters A, Ahmann A, Battelino T et al. Diabetes Technology—Continuous Subcutaneous Insulin Infusion Therapy and Continuous Glucose Monitoring in Adults: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2016:jc.2016-2534.

4 Šoupal J, Petruželková L, Flekač M et al. Comparison of Different Treatment Modalities for Type 1 Diabetes, Including Sensor-Augmented Insulin Regimens, in 52 Weeks of Follow-Up: A COMISAIR Study. Diabetes Technology & Therapeutics. 2016;18(9):532-538.

5 Battelino T PM, Bratina N, Nimri R, Oskarsson P, Bolinder J. Effect of Continuous Glucose Monitoring on Hypoglycemia in Type 1 Diabetes. Diabetes Care. 2011;34(4):795-800.

6 Beck RW, Riddlesworth T, Ruedy K, et al. Effect of continuous glucose monitoring on glycemic control in adults with type 1 diabetes using insulin injections: The DIAMOND randomized clinical trial. JAMA. 2017; 317(4); 371-378.

7 Choudhary P, Ramasamy S, Green L et al. Real-Time Continuous Glucose Monitoring Significantly Reduces Severe Hypoglycemia in Hypoglycemia-Unaware Patients With Type 1 Diabetes. Diabetes Care. 2013;36(12):4160-4162.

8 Lind M, Polonsky, W, Hirsch, I, et al. Continuous Glucose Monitoring vs Conventional Therapy for Glycemic Control in Adults With Type 1 Diabetes Treated With Multiple Daily Injections – The GOLD Randomized Clinical Trial. [published January 2017]. JAMA.

9 Haas L, Maryniuk M, Beck J, et al. National Standards for Diabetes Self-Management Education and Support, Diabetes Care, Volume 35, November 2012

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